![]() ![]() Our findings indicate that having an episode of TGA does not increase the risk of subsequent cerebrovascular events, seizures, or cognitive impairment.Ĭopyright © 2016 Mayo Foundation for Medical Education and Research. Modified Rankin scale and death rates at last follow-up were also similar between both groups. The amnesia typically remits spontaneously but may recur. EEG examination the technician spoke to the patient, who was able to carry on a normal conversation. Diagnosis is primarily clinical but includes laboratory tests and CT, MRI, or both. The TGA recurrence occurred in 5.4% of patients after a median interval of 4.21 years (interquartile range, 2.82-8.44). Treatment Key Points Transient global amnesia is anterograde and usually retrograde amnesia that begins suddenly and lasts up to 24 hours. Transient global amnesia (TGA) is an uncommon clinical syndrome characterized by short-term memory loss and disorientation that resolves in 24 h. Tips to help enhance memory and get support can help people with amnesia and their families cope. There's no specific treatment for amnesia, but treatment can be directed at the underlying cause. There was no statistically significant difference between survival curves for the TGA group and the control group using time to any type of cerebrovascular event (log-rank P=.30), time to seizures event (log-rank P=.55), and time to cognitive impair event (log-rank P=.88) as end points. Unlike a temporary episode of memory loss, called transient global amnesia, amnesia can be permanent. Previous migraine was more common in the TGA group (42 patients vs 12 patients P<.001). Prevalence of vascular risk factors and history of seizures were similar between both groups. The mean duration of follow-up was 12 years in both groups (range, 0.07-29.93). Transient global amnesia is a benign self-resolving condition characterized by anterograde amnesia that resolves in less than 24 h with no associated neurologic deficit. End points were studied using Kaplan-Meier survival plots and log-rank test.Ī total of 221 patients with TGA were identified and 221 age- and sex-matched controls were included in the analysis. End points were cerebrovascular event (stroke or transient ischemic attack), seizure, or cognitive impairment (mild cognitive impairment or dementia) during follow-up. Transient global amnesia was defined clinically. To study the long-term risk of cerebrovascular events, seizures, and cognitive impairment in patients with transient global amnesia (TGA).ĭata for all patients diagnosed with possible TGA in Olmsted County, Minnesota, between January 1, 1985, through December 31, 2010, were retrieved from the Rochester Epidemiology Project database. ![]()
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